منابع مشابه
Dmd057224 839..843
It has been proposed that in humans 4b-hydroxycholesterol is formed mainly by CYP3A-catalyzed metabolism of cholesterol and thus may serve as an endogenous marker for CYP3A activity. The cynomolgus monkey is widely used as one of the nonrodent preclinical safety species in pharmaceutical research. In the current study, the potential application of 4b-hydroxycholesterol as an endogenous biomarke...
متن کاملDmd057224 839..843
It has been proposed that in humans 4b-hydroxycholesterol is formed mainly by CYP3A-catalyzed metabolism of cholesterol and thus may serve as an endogenous marker for CYP3A activity. The cynomolgus monkey is widely used as one of the nonrodent preclinical safety species in pharmaceutical research. In the current study, the potential application of 4b-hydroxycholesterol as an endogenous biomarke...
متن کامل833-839 Kambadur_Muralidhar
INTRODUCTION Discovery of hormones and endocrine phenomena: Experimental work in endocrinology is an excellent example for the reductionist view of biology. This view point, which is currently in fashion, asserts that the laws of physics and chemistry are sufficient to understand and to ‘explain’ biological phenomena. While this statement will not be discussed any further, it cannot be helped s...
متن کاملEvidence against Hormonal Control of Integumentary Water Loss in Periplaneta Americana
The effect of decapitation on water loss from adult male cockroaches was studied in order to re-examine the possibility of hormonal modulation of integumental permeability. We found no effect of decapitation on the permeability or water content in measurements made on the pronotum. Although overall weight losses of the decapitated animals always exceeded those of intact animals, loss rates and ...
متن کاملHemifacial Spasm : MR Imaging Features 839
MR imaging was used to evaluate the relationship of the root exit zone of the seventh cranial nerve to surrounding vascular structures in 13 patients with clinically documented hemifacial spasm and in 70 asymptomatic patients. MR imaging clearly demonstrated the course of the seventh nerve from the root exit zone of the brainstem to the internal auditory canal and its relationship to the surrou...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1978
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197804001-00844